Table 1 The top 10 R groups in library
From: IntelliPatent: a web-based intelligent system for fast chemical patent claim drafting
| R group | SMILES | Occurrence (%) |
|---|---|---|
| Methyl | *C | 19.9 |
| Fluoro | *F | 8.4 |
| Methoxy | *OC | 7.0 |
| Hydroxy | *O | 6.3 |
| Sulfamoyl | *S(=O)(=O)N | 5.6 |
| Chloro | *Cl | 5.1 |
| Hydrogen | *H | 3.8 |
| Ethynyl | *C#C | 2.8 |
| Trifluoromethyl | *C(F)(F)F | 2.2 |
| Carboxy | *C(=O)O | 1.9 |