Table 1 Statistics for each of the five transformer modules: (1) EC-based module (Enzyme Commission-based metabolism); (2) CYP450 module (Cytochrome P450 metabolism); (3) human gut microbial module (Human gut microbial metabolism); (4) Phase II module (Phase II metabolism), and (5) environmental microbial module (Environmental microbial degradation)
| Number of enzymes | Number of biotransformation rules | Number of enzyme-rule associations | Number of covered biosystems | |
|---|---|---|---|---|
| EC-based (ecbased) | 285 | 408 | 459 | 2 |
| CYP450 (cyp450) | 9 | 163 | 712 | 1 |
| Human gut microbial (hgut) | 53 | 201 | 204 | 2 |
| Phase II (phaseII) | 9 | 74 | 81 | 2 |
| Environmental microbial (envmicro) | 1 | 301 | 301 | 1 |